So much about KRYSTEXXA is different from other gout medicines: The way it works, the treatment process, and the support that’s offered every step of the way to answer your questions, help you prepare for your treatments, and follow up with you after. We’re all in this together.

YOUR FIRST POINT OF
CONTACT WITH US

Gout Nurse Advocate Logo

Whether you learned about KRYSTEXXA from your doctor or an online search, Gout Nurse Advocates can help you better understand out-of-control chronic gout and how KRYSTEXXA may help. Gout Nurse Advocates do not provide individual patient care or medical advice.

Call 833-4MY-GOUT

Reach out Monday - Friday from 
8:00 AM to 8:00 PM ET at 833-469-4688.

As soon as your doctor or gout specialist prescribes KRYSTEXXA and confirms your insurance coverage, you can connect with a dedicated Patient Access Manager (PAM) as much or as little as you'd like for help navigating your coverage and learning what to expect before and after each KRYSTEXXA IV treatment.

REQUEST A PAM

YOUR PARTNER THROUGHOUT
TREATMENT

Patient Access Manager Logo

GET TO KNOW US

WATCH KHASH’S PAM STORY

“A great gal by the name of Lindsey reached out to me.”

Read transcript

Khash:

When I was a young adult, I started noticing some of the characteristics of what later on became gout. Well, as time progressed, I felt like my gout was becoming more and more out of control. I get a phone call from my doctor and he calls me to discuss gout with me. And I'm like, "Great, I've been dealing with this 25 years plus."

Khash:

... and said, listen, we have this drug to help combat your gout. Are you open to it?" I said, "Yes." He was like, "We'll have a patient access manager get in contact with you to discuss it further with you."

Lindsey:

Once you have the pre-medications in your system, the nurse is going to mix the KRYSTEXXA into an IV fluids bag. She's going to hang that up above your chair, start an IV, and the medication is going to infuse over two hours.

Khash:

My patient access manager, Lindsey, really took the time to explain it all to me.

Lindsey:

But after you get this first dose of KRYSTEXXA, in two weeks or two days before the next dose of KRYSTEXXA, you're going to go to the lab, you're going to get your blood drawn and they're going to measure your serum uric acid level. Okay?

Khash:

She went over that KRYSTEXXA was IV therapy. Initially, while we're combating it in your body, if you see any tophi, if you see anything, know that it's like a glacier. If you notice tophi on your skin, underneath it is 10 years of buildup to lead to that point. Initially, as we're attacking that, it's going to cause more flareups, more inflammation. I'm like, "That's fine," because I've been dealing with that all these years. But I know that it's because it's a response to us dealing with the problem and getting uric acid and gout and the tophi out of my body. I'm 100% for it.

Khash:

It's a big commitment on my time, but given the severity of it and dealing with what I've had to deal with for 25 years or so, that seems small in comparison. Tomorrow's going to be my first IV therapy, so I'm looking forward to that. And it makes me look forward to the next 30, 40 years without having to deal with the same issues.

Lindsey:

You're going to have a whole team of professional nurses there to be watching you and monitoring you to make sure that you're safe.

Khash:

Excellent.

Lindsey:

Okay?

Speaker 3:

Indication and important safety information. Use, KRYSTEXXA (pegloticase) is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments. Important safety information, what is the most important information I should know about KRYSTEXXA (pegloticase)? Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life threatening and usually happen within two hours of the infusion. KRYSTEXXA should be given to you by a doctor or nurse in a healthcare setting where serious allergic reactions can be treated. Your doctor or nurse should watch you for any signs of a serious allergic reaction during and after your treatment with KRYSTEXXA. Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with KRYSTEXXA: wheezing, shortness of breath, cough, chest tightness, chest pain, or trouble breathing, dizziness, fainting, fast or weak heartbeat, or feeling nervous, reddening of the face, itching, hives, rash, or feeling warm, swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing.

Speaker 3:

Who should not receive KRYSTEXXA? Do not receive KRYSTEXXA if you have a rare blood problem called glucose 6-phosphate dehydrogenase (G6PD) deficiency or favism. Your doctor should test you for G6PD before you start KRYSTEXXA. KRYSTEXXA is not recommended if you have high levels of uric acid without a history of gout. Before you receive KRYSTEXXA, tell your doctor if you know you have G6PD deficiency, ever had any heart problems or high blood pressure, are pregnant or planning to become pregnant, it is not known if KRYSTEXXA will harm your unborn baby, are breastfeeding or plan to breastfeed. It is not known if KRYSTEXXA passes into your breast milk. Tell your doctor about all the medicines you take.

Speaker 3:

Do not take any other uric acid lowering drug such as allopurinol or febuxostat (Uloric®) while taking KRYSTEXXA. Prior to your treatment with KRYSTEXXA, your doctor may give you medicine to help reduce your chance of getting a reaction. Take these medicines as directed by your doctor or nurse. Your doctor will also test your uric acid levels prior to each treatment to monitor your response to KRYSTEXXA.

Speaker 3:

What are the possible side effects of KRYSTEXXA? Please review important information section above. The most common side effects in patients taking KRYSTEXXA were gout flare ups or attacks, allergic reactions, nausea, bruising, sore throat, constipation, chest pain, and vomiting. This is not a complete list of all possible side effects. Tell your doctor or treatment team if you have any side effect that bothers you or that does not go away. Please see the medication guide and prescribing information for more information. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch or call the FDA at 1-800-FDA-1088.

REAL PATIENTS YOU CAN
TALK WITH ANYTIME

Peer Mentor Logo

Our peer mentors will tell you what KRYSTEXXA has been like for them. They volunteer because they want to help others the same way they’ve been helped.

Request a peer mentor

WATCH ED’S PEER
MENTOR STORY

“My purpose is to make life better for other people.”

Read transcript

Ed:

I've been living with gout for quite a long time, 17 years. There's the physical pain and then there's the emotional pain, and the emotional pain is something that lingers. The shame that I felt of what I looked like with my hands and my elbows. All the doctors that I saw that misdiagnosed me and all they did was treat my symptoms. When KRYSTEXXA came along for me, little by little, I saw the results and I began to feel better.

Ed:

I wanted to share how KRYSTEXXA helped me. Most of the patients that I've been mentoring are considering taking KRYSTEXXA. They have a lot of questions, there's a lot of unknown. Occasionally I'll talk to a patient who's already on KRYSTEXXA and they don't like the results right away and so they think about giving it up. Most of the patients with whom I've spoken are looking for that connection with somebody who really understands. Sometimes my conversation with the mentees does get emotional, as soon as I start talking about ... Say, "All the knuckles on my hand were swollen, I couldn't wear my wedding ring for eight years and I finally got that on." That's a strong connection.

Tom:

For the past 20 years I've been battling an out of control experience with gout. It's crippling, both emotionally and physically. I was introduced to KRYSTEXXA when the doctor said that the gout was an enzyme issue. So, I Googled enzyme therapy for gout, that's how I found KRYSTEXXA. The first treatment I had with KRYSTEXXA, I came out feeling magnificent, but after a few days, it became the same old, same old pain in the joints and I was really concerned about that. On the website, it said, "We have a peer mentor program," and that's when I was able to connect via telephone with Ed.

Ed:

When I first talked to Tom, I began to share some of my story. The first two months of my treatment, it increased the number of flares that I had, but then slowly the pain began to subside.

Tom:

That really helped me just to go, "Relax, I'm going to get through this." It was just a blessing, really. He continued guiding me through what to expect with KRYSTEXXA. I felt a sense of clarity, a sense of purpose and a sense of direction to continue with the process. Ed.

Ed:

Tom. And that takes courage, I would have had a hard time even reaching out to somebody else in the same manner. Today is the first time I've ever met a patient that I have been mentor for. I'm talking to a real person that had real pain and has real struggle and I identify with that.

Tom:

... say just somebody else's experience really helped me, but it really did. When I first met Ed in person, it just uplifted me and he's a really great man. Being able to talk with a peer mentor who was on the other side of chronic gout meant a lot to me.

Ed:

Reconnecting with other people is going to put you into situations which is going to give you energy and life back again.

Tom:

Yes.

Ed:

When I talk to a patient in the mentor program, I feel like that I'm investing a part of me, in them. I had shirts, I had polar shirts made with ... They would come down to here to cover up my elbows. One of the amazing things about this mentor program is that one stranger reaches out to another and began to create a bond that is totally different than the bond they have with their spouse, their family members, their doctor. My purpose in life is to make life better for other people. I feel like I'm achieving some of what I'm here for.

Narrator:

Indication and important safety information. Use, KRYSTEXXA (pegloticase) is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments. Important safety information, what is the most important information I should know about KRYSTEXXA (pegloticase)? Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life threatening and usually happen within two hours of the infusion. KRYSTEXXA should be given to you by a doctor or nurse in a healthcare setting where serious allergic reactions can be treated. Your doctor or nurse should watch you for any signs of a serious allergic reaction during and after your treatment with KRYSTEXXA. Tell your doctor or nurse right away, if you have any of these symptoms during or after your treatment with KRYSTEXXA, wheezing, shortness of breath, cough, chest tightness, chest pain, or trouble breathing, dizziness, fainting, fast or weak heartbeat, or feeling nervous. Reddening of the face, itching, hives, rash, or feeling warm, swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing.

Narrator:

Who should not receive KRYSTEXXA? Do not receive KRYSTEXXA if you have a rare blood problem called glucose 6-phosphate dehydrogenase, (G6PD) deficiency or favism. Your doctor should test you for G6PD before you start KRYSTEXXA. KRYSTEXXA is not recommended if you have high levels of uric acid without a history of gout. Before you receive KRYSTEXXA, tell your doctor, if you know you have G6PD deficiency. Ever had any heart problems or high blood pressure are pregnant or planning to become pregnant, it is not known if KRYSTEXXA will harm your unborn baby. Are breastfeeding or plan to breastfeed, it is not known if KRYSTEXXA passes into your breast milk, tell your doctor about all the medicines you take.

Narrator:

Do not take any other uric acid lowering drug such as allopurinol or febuxostat (Uloric®) while taking KRYSTEXXA. Prior to your treatment with KRYSTEXXA, your doctor may give you medicine to help reduce your chance of getting a reaction. Take these medicines as directed by your doctor or nurse. Your doctor will also test your uric acid levels prior to each treatment, to monitor your response to KRYSTEXXA. What are the possible side effects of KRYSTEXXA? Please review important information section above. The most common side effects in patients taking KRYSTEXXA were gout flare ups or attacks, allergic reactions, nausea, bruising, sore throat, constipation, chest pain, and vomiting. This is not a complete list of all possible side effects. Tell your doctor or treatment team if you have any side effect that bothers you or that does not go away. Please see the medication guide and prescribing information for more information. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call the FDA at 1-800-FDA-1088.


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IMPORTANT SAFETY INFORMATION

Intended for U.S residents only.

What is the most important information I should know about KRYSTEXXA (pegloticase)?

Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life threatening and usually happen within 2 hours of the infusion.

USE

KRYSTEXXA is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about KRYSTEXXA (pegloticase)?

Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life threatening and usually happen within 2 hours of the infusion.

KRYSTEXXA should be given to you by a doctor or nurse in a healthcare setting where serious allergic reactions can be treated. Your doctor or nurse should watch you for any signs of a serious allergic reaction during and after your treatment with KRYSTEXXA.

Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with KRYSTEXXA:

  • Wheezing, shortness of breath, cough, chest tightness, chest pain, or trouble breathing
  • Dizziness, fainting, fast or weak heartbeat or feeling nervous
  • Reddening of the face, itching, hives, rash, or feeling warm
  • Swelling of the throat or tongue, throat tightness, hoarse voice or trouble swallowing

Who should not receive KRYSTEXXA?

Do not receive KRYSTEXXA if you have a rare blood problem called glucose 6-phosphate dehydrogenase (G6PD) deficiency or favism. Your doctor should test you for G6PD before you start KRYSTEXXA.

KRYSTEXXA is not recommended if you have high levels of uric acid without a history of gout.

Before you receive KRYSTEXXA, tell your doctor if you:

  • Know you have G6PD deficiency
  • Ever had any heart problems or high blood pressure
  • Are pregnant or planning to become pregnant. It is not known if KRYSTEXXA will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if KRYSTEXXA passes into your breast milk

Tell your doctor about all the medicines you take. Do not take any other uric acid lowering drug, such as allopurinol or febuxostat (Uloric®), while taking KRYSTEXXA.

Prior to your treatment with KRYSTEXXA, your doctor may give you medicine to help reduce your chance of getting a reaction. Take these medicines as directed by your doctor or nurse. Your doctor will also test your uric acid levels prior to each treatment to monitor your response to KRYSTEXXA.

What are the possible side effects of KRYSTEXXA?

Please review important information section above. The most common side effects in patients taking KRYSTEXXA were gout flare-ups or attacks, allergic reactions, nausea, bruising, sore throat, constipation, chest pain, and vomiting.

This is not a complete list of all possible side effects. Tell your doctor or treatment team if you have any side effect that bothers you or that does not go away.

Please see the Medication Guide and Prescribing Information for more information. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call the FDA at 1-800-FDA-1088.

IMPORTANT SAFETY INFORMATION

Intended for U.S residents only.

What is the most important information I should know about KRYSTEXXA (pegloticase)?

Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life threatening and usually happen within 2 hours of the infusion.

USE

KRYSTEXXA is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about KRYSTEXXA (pegloticase)?

Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life threatening and usually happen within 2 hours of the infusion.

KRYSTEXXA should be given to you by a doctor or nurse in a healthcare setting where serious allergic reactions can be treated. Your doctor or nurse should watch you for any signs of a serious allergic reaction during and after your treatment with KRYSTEXXA.

Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with KRYSTEXXA:

  • Wheezing, shortness of breath, cough, chest tightness, chest pain, or trouble breathing
  • Dizziness, fainting, fast or weak heartbeat or feeling nervous
  • Reddening of the face, itching, hives, rash, or feeling warm
  • Swelling of the throat or tongue, throat tightness, hoarse voice or trouble swallowing

Who should not receive KRYSTEXXA?

Do not receive KRYSTEXXA if you have a rare blood problem called glucose 6-phosphate dehydrogenase (G6PD) deficiency or favism. Your doctor should test you for G6PD before you start KRYSTEXXA.

KRYSTEXXA is not recommended if you have high levels of uric acid without a history of gout.

Before you receive KRYSTEXXA, tell your doctor if you:

  • Know you have G6PD deficiency
  • Ever had any heart problems or high blood pressure
  • Are pregnant or planning to become pregnant. It is not known if KRYSTEXXA will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if KRYSTEXXA passes into your breast milk

Tell your doctor about all the medicines you take. Do not take any other uric acid lowering drug, such as allopurinol or febuxostat (Uloric®), while taking KRYSTEXXA.

Prior to your treatment with KRYSTEXXA, your doctor may give you medicine to help reduce your chance of getting a reaction. Take these medicines as directed by your doctor or nurse. Your doctor will also test your uric acid levels prior to each treatment to monitor your response to KRYSTEXXA.

What are the possible side effects of KRYSTEXXA?

Please review important information section above. The most common side effects in patients taking KRYSTEXXA were gout flare-ups or attacks, allergic reactions, nausea, bruising, sore throat, constipation, chest pain, and vomiting.

This is not a complete list of all possible side effects. Tell your doctor or treatment team if you have any side effect that bothers you or that does not go away.

Please see the Medication Guide and Prescribing Information for more information. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call the FDA at 1-800-FDA-1088.