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KRYSTEXXA is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments. Read More

Personalized Support for You

Amgen By Your Side is a patient support program designed specifically for patients prescribed KRYSTEXXA. Our dedicated team is your partner, committed to providing nonmedical, personalized support to help as you start and continue on treatment as prescribed by your doctor.

COMMERCIALLY INSURED PATIENTS MAY PAY AS LITTLE AS $0 PER DOSE* FOR KRYSTEXXA

*through the Amgen Commercial Co-Pay Program.

  • Personalized Support

  • Insurance Coverage and Financial Support

  • Preparing for Treatment

Personalized Support for Patients

The Amgen By Your Side team is led by a Patient Access Liason (PAL). The PAL is a dedicated support partner who helps investigate, explain, and educate on the steps in your treatment experience. They are your partner to support and champion you while accomplishing your treatment goals.

Get Personalized Resources and Support

Insurance and Managing Costs

The insurance approval for KRYSTEXXA may seem confusing at first. However, your PAL can help you make sense of the process. Our insurance review will likely include

Benefits Investigation and Summary of Benefits:

  • Details of your insurance coverage criteria for KRYSTEXXA
  • Estimate of your potential out-of-pocket costs and help with understanding possible financial-support options
  • Whether your doctor needs to submit a prior authorization

Your PAL can stay in touch with you throughout the process and update you on the status of your insurance review. Additionally, your PAL can help you learn about steps you can take to keep the process moving, including completing any required labs and following up with your physician to see if additional information is needed for the prior authorization process.

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Treatment Planning From Start to Finish

The Amgen By Your Side team can help you plan, coordinate, and manage your ongoing
infusion schedule. A Patient Access Liaison (PAL) will work to understand your individual needs. We will partner with you to coordinate appointments, find infusion center locations, and prepare for upcoming appointments, from your first infusion to your last. We will be by your side, striving to empower you to be focused, motivated, and committed to maintaining your treatment goals.

Learn More
  • Personalized Support

    Personalized Support You Can Count On

    The Amgen By Your Side team is led by a Patient Access Liason (PAL). The PAL is a dedicated support partner who helps investigate, explain, and educate on the steps in your treatment experience. They are your partner to support and champion you while accomplishing your treatment goals.

    Get Personalized Resources and Support
  • Insurance Coverage and Financial Support

    Insurance and Managing Costs

    The insurance approval for KRYSTEXXA may seem confusing at first. However, your PAL can help you make sense of the process. Our insurance review will likely include

    Benefits Investigation and Summary of Benefits:

    • Details of your insurance coverage criteria for KRYSTEXXA
    • Estimate of your potential out-of-pocket costs and help with understanding possible financial-support options
    • Whether your doctor needs to submit a prior authorization

    Your PAL can stay in touch with you throughout the process and update you on the status of your insurance review. Additionally, your PAL can help you learn about steps you can take to keep the process moving, including completing any required labs and following up with your physician to see if additional information is needed for the prior authorization process.

    Explore Resources
  • Preparing for Treatment

    Treatment Planning From Start to Finish

    The Amgen By Your Side team can help you plan, coordinate, and manage your ongoing
infusion schedule. A Patient Access Liaison (PAL) will work to understand your individual needs. We will partner with you to coordinate appointments, find infusion center locations, and prepare for upcoming appointments, from your first infusion to your last. We will be by your side, striving to empower you to be focused, motivated, and committed to maintaining your treatment goals.

    Learn More

Hear how a Patient Access Liaison can help you on your journey

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The Amgen By Your Side team is here for you

Visit Amgen By Your Side

For more information, or if you have specific questions, call 833-842-8477.

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Patient Stories.

See how real patients took back control of gout with KRYSTEXXA.

USE AND IMPORTANT SAFETY INFORMATION

What is the most important information I should know about KRYSTEXXA® (pegloticase)?

Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life-threatening and usually happen within 2 hours of the infusion.

KRYSTEXXA should be given to you by a doctor or nurse in a healthcare setting where serious allergic reactions can be treated. Your doctor or nurse should watch you for any signs of a serious allergic reaction during and after your treatment with KRYSTEXXA.

Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with KRYSTEXXA:

  • wheezing, shortness of breath, cough, chest tightness, chest pain, or trouble breathing
  • dizziness, fainting, fast or weak heartbeat or feeling nervous
  • reddening of the face, itching, hives, or feeling warm
  • swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing

Who should not receive KRYSTEXXA?

Do not receive KRYSTEXXA if you:

  • have a rare blood problem called glucose-6-phosphate dehydrogenase (G6PD) deficiency or favism. Your doctor may test you for G6PD before you start KRYSTEXXA.
  • have had a serious allergic reaction to KRYSTEXXA or any of its ingredients. See the end of the Medication Guide for a complete list of ingredients in KRYSTEXXA.

What should I tell my doctor before receiving treatment with KRYSTEXXA?

Before you receive KRYSTEXXA, tell your doctor about all of your medical conditions, including if you:

  • ever had any heart problems or high blood pressure.
  • are pregnant or plan to become pregnant. It is not known if KRYSTEXXA will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if KRYSTEXXA passes into your breast milk. You and your doctor should decide if you will receive KRYSTEXXA or breastfeed.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not take any other uric acid lowering drug, such as allopurinol, febuxostat (Uloric), or probenecid, while receiving KRYSTEXXA.

KRYSTEXXA is recommended to be given with another prescription medicine called methotrexate. KRYSTEXXA may also be used alone. You and your doctor will decide the treatment that is right for you.

Prior to your treatment with KRYSTEXXA, your doctor may give you medicine to help reduce your risk of getting gout flares or an allergic reaction. Take these medicines as directed by your doctor or nurse. Your doctor will also test your uric acid levels prior to each treatment to monitor your response to KRYSTEXXA.

Your gout flares may increase in the first 3 months when you start receiving KRYSTEXXA. It’s important to understand that this is happening because KRYSTEXXA is breaking down uric acid in your body. Do not stop receiving KRYSTEXXA even if you have a flare, as the amount of flares will decrease after 3 months of treatment. Your doctor may give you other medicines to help reduce your gout flares for the first few months after starting KRYSTEXXA.

What are the possible side effects of KRYSTEXXA?

In KRYSTEXXA clinical trials:
The most common side effects of KRYSTEXXA when given together with methotrexate were
gout flares, joint pain, coronavirus disease 2019 (COVID-19), nausea, and fatigue.
The most common side effects of KRYSTEXXA were gout flares, allergic reactions (including infusion reactions). See “What is the most important information I should know about KRYSTEXXA?”, nausea, bruising, sore throat, constipation, chest pain, coronavirus disease 2019 (COVID-19), and vomiting.
This is not a complete list of all possible side effects. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch or call 1-800-FDA-1088.

For additional Important Safety Information, please see the Full Prescribing Information, including Boxed Warning and Medication Guide and discuss with your doctor.

USE

KRYSTEXXA is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments.

KRYSTEXXA is not for use in people with too much uric acid in their bodies who do not have symptoms (asymptomatic hyperuricemia).

USE AND IMPORTANT SAFETY INFORMATION

What is the most important information I should know about KRYSTEXXA® (pegloticase)?

Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life-threatening and usually happen within 2 hours of the infusion.